Supplement Resource

Vitamin E This may help with hot flashes and anxiety. 800 IU of vitamin E per day can be used.

Vitamin C This may help with hot flashes and can be used up between 500 to 5000 mg per day.

Calcium and Magnesium This may help with mental stress and anxiety. 500 mg of calcium can be used per day along with 250 to 300 mg of magnesium per day.

B Complex Vitamins These may help with hot flashes and mood issues also. A B complex vitamin that provides between up to 50 mg of vitamin B6, up to 100 mcg of vitamin B12, and up to 1000 mcg of folic acid can be used.

Evening Primrose Oil This can help with hot flashes. Up to 1200 mg of evening primrose oil can be used.

Flaxseed Oil May also be helpful with control of hot flashes, 1 to 2 tablespoons of flaxseed oil per day can be used.

Black Cohosh This may help with hot flashes, vaginal dryness, and mood issues such as depression. It may also be helpful for palpitations. 500-mg capsules of one to three per day can be used. A tincture of black cohosh can also be used from Gaia Herbs between 10 to 25 drops of black cohosh can be used each day every four hours. 

Dong Quai Can also be used to help with hot flashes. Approximately 600 mg per day can be used or 5 to 20 drops of a tincture up to three times per day can be used.

Vitex This can also be helpful in the treatment of hot flashes, night sweats. It may also be useful for women with peri menopausal heavy and irregular periods. 200 mg of Vitex can be used one to three times daily. A tincture can also be used.

Maca In doses of 1,000-2,000 mg per day it may be helpful.

Red Clover may help with hot flashes, vaginal dryness, depression and anxiety. 40mg of an extract can be used two times per day.

Pueraria mirifico This is a member of the legume family and contains phytoestrogens. Between 50 to 100mg daily may help with hot flashes and night sweats.

5-hydroxy tryptophan 5-HT can help to balance serotonin and boost it. It should be used with caution in women who use SSRI’s. It may help to improve mood and relieve insomnia. 100mg can be used two to three times a day.

Cumin, Coriander and Fennel Tea Combine ½ teaspoon of each into quart of boiling water; steep and strain.

Green Tea and Dark Chocolate These may help with stress and anxiety. Green tea contains L-theanine that may help to induce quiet and calm.

Saffron 15mg two times per day may help with anxiety, irritability, depression, mood swings, and insomnia.

Inositol is a dietary supplement that has shown some benefit for PCOS (polycystic ovarian syndrome). There are 9 forms (stereoisomers) of inositol, however the commonly used term inositol generally refers to the most common form, myo-inositol. Inositols are naturally found in the highest concentrations in whole grains, beans, nuts and citrus fruits. IIt is also naturally  made in the body. Studies have shown that inositol improves the way the body uses insulin, promotes normal hormone levels, resulting in more regular menstrual cycles and normal ovarian function, normalizing lipid levels and helps with egg quality. It may also help with weight loss. In women with PCOS, a high percentage of women taking myo-inositol will establish regular periods and show evidence of ovulation

Myo- inositol may help some women with PCOS and can help with restoration of more normal blood sugar levels, testosterone levels, and lipid levels. It can therefore help with excess hair growth, acne, and also improve ovulation. It also may help with fertility, anxiety, and depression. It may also be beneficial for PMS. Women with PCOS appear to benefit more from a combination of isomers of inositol, in a ration of 40:1 of myo-inositol to D-chiro-inositol. Other ratios of inositol isomers are undergoing clinical investigation currently.

A recent study published in February 2015 again demonstrated the effectiveness of myo-inositol in patents with PCOS. Fifty women with PCOS, insulin resistance and lack of ovulation were given myo-inositol. Twenty-nine of the 50 women showed evidence of ovulation and 11 (37.9%) became pregnant. In the patients who did not ovulate on myo-inositol alone, 13 of the 18 showed an ovulatory response when clomiphene was added and six (42.6%) conceived.

Extensive research supports the use of myo-inositol in PCOS. Its effects may be additive to metformin.

In addition to PCOS, myo-inositol has been used in the treatment of diabetic neuropathy, depression, Alzheimer’s disease, and panic disorder. myo-inositiol is well tolerated and appears safe when used at doses up to 12 grams per day.

Common side effects may include nausea fatigue, dizziness and insomnia.

Resources:

Ovasitol is a supplement formulated specifically for women with PCOS. It contains myo and d-chiro inositol in the ratio 40:1. Ovasitol also contains maltodextrin. This is a carbohydrate, made from starch that is used for thickening. The addition of maltodextrin means that some people are more likely to experience side effects, such as diarrhea, nausea and constipation. If this happens to you, you might want to try another inositol product before giving up on inositol altogether.

Sensitol™ is a formulation comprised of myo-inositol (MI) and D-chiro-inositol (DCI) - along with alpha lipoic acid.

NAD and BASIS: As we age, levels of NAD fall. NAD support may lead to a prolonged health span. Elevating NAD levels in mice can slow down the aging process and help them to love longer. The question remains if these results can be translated into humans. There is one supplement on the market from the company ELYSIUM that has been demonstrated in a randomized trial to increase NAD levels in humans.

BASIS from ELYSIUM contains: 

Nicotinamide Riboside, 250mg
A direct precursor to the coenzyme NAD.

Pterostilbene, 50mg
A bioavailable polyphenol similar to resveratrol, but more bioavailable. Pterostilbene is created by plants to protect against internal and external stresses.